TWST
Twist Bioscience Corporation Healthcare - Synthetic Biology Investor Relations →
Twist Bioscience Corporation (TWST) closed at $87.56 as of 2026-06-19, trading 149.4% above its 200-week moving average of $35.11. The stock moved further from the line this week, up from 118.4% last week. With a 14-week RSI of 80, TWST is in overbought territory.
Trading volume is running at 1.9x of its 14-week average, which is in the normal range. The balance between buying and selling volume (1.33 ratio) is neutral — neither side is clearly dominating.
Over the past 350 weeks of data, TWST has crossed below its 200-week moving average 4 times. On average, these episodes lasted 56 weeks. Historically, investors who bought TWST at the start of these episodes saw an average one-year return of +171.5%.
With a market cap of $5.5 billion, TWST is a mid-cap stock. Free cash flow yield is currently negative, meaning the company is burning cash. Return on equity stands at -18.2%. The stock trades at 12.0x book value.
Share count has increased 7.3% over three years, indicating dilution.
Over the past 6.8 years, a hypothetical investment of $100 in TWST would have grown to $346, compared to $271 for the S&P 500. That represents an annualized return of 20.2% vs 15.9% for the index — confirming TWST as a market-beating investment and the kind of quality company where buying during 200-week moving average touches has historically been rewarded.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Business Health
Annual financials — how the underlying business has performed over the past several years.
Cash Flow Free cash flow & net income ($M)
Revenue Annual revenue ($M) — business growth proxy
Total Debt Balance sheet debt ($M)
ROIC Return on invested capital (%)
FCF Yield Free cash flow / market cap (%) — Yartseva signal
Gross Margin Pricing power & competitive moat (%)
Shares Outstanding Buybacks vs dilution (millions)
Growth of $100: TWST vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After TWST Crosses Below the Line?
Across 4 historical episodes, buying TWST when it crossed below its 200-week moving average produced an average return of +118.5% after 12 months (median +203.0%), compared to +19.0% for the S&P 500 over the same periods. 75% of those episodes were profitable after one year. After 24 months, the average return was +135.3% vs +49.7% for the index.
Each line shows $100 invested at the moment TWST crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Bean Score Experimental
The Bean Score measures how far a stock's free cash flow yield has deviated from its own quarterly baseline, normalized by the stock's historical behavior. TWST currently has negative free cash flow, so price-based dislocation levels are not available. The score still tracks yield deviation from baseline.
Quarterly FCF & Yield Trailing twelve-month free cash flow and yield at each quarter end
Signal Accuracy Collecting Data
The Bean Score system is accumulating weekly data to validate signal accuracy. After 13+ weeks of history, this section will display win rates and average returns for each σ threshold crossing — answering the question: "When this score says cheap or expensive, does the price subsequently move in the expected direction?"
Theoretical framework — not backtested or forward-tested. The Bean Score uses trailing twelve-month free cash flow yield as a dislocation identifier. It measures whether the market has pushed a stock's yield unusually far from its own baseline behavior. These levels are reference points for identifying potential swing trade opportunities, not buy/sell signals. FCF values update quarterly with earnings; between reports, all movement is price-driven.
Dislocation Scores Experimental
Each score measures deviation from TWST's own historical baseline — the same idea as the Bean Score, applied to different fundamentals. Positive means cheaper or more dislocated than this stock's norm. Scores marked σ are normalized by the stock's own variability; pp values are simple deltas from its recent baseline.
Theoretical framework — not backtested. These scores describe how unusual today's readings are for this specific company. They are starting points for research, not buy or sell signals. Annual-statement scores (buyback, accruals, FCF vs history) rest on only ~4 yearly data points and are deltas, not sigmas.
Historical Touches
TWST has crossed below its 200-week MA 4 times with an average 1-year return of +171.5% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Oct 2019 | Feb 2020 | 17 | 16.6% | +295.6% | +286.4% |
| Mar 2020 | Mar 2020 | 1 | 5.6% | +443.6% | +265.3% |
| Jan 2022 | Jan 2025 | 158 | 80.9% | -56.6% | +46.4% |
| Feb 2025 | Jan 2026 | 47 | 34.7% | +3.2% | +84.0% |
| Average | 56 | — | +171.5% | — |
Frequently Asked Questions
Is TWST below its 200-week moving average?
No. Twist Bioscience Corporation (TWST) is currently 149.4% above its 200-week moving average of $35.11. It would need to fall to $35.11 to cross below the line.
What is TWST's 200-week moving average price?
Twist Bioscience Corporation's 200-week moving average is $35.11 as of 2026-06-19. This is the average weekly closing price over roughly the last 4 years, and it acts as a long-term trend line. When a stock drops below this level, it can signal that the price has fallen far enough from the long-term trend to attract value-oriented investors.
What happens when TWST drops below its 200-week moving average?
TWST has crossed below its 200-week moving average 4 times in our data. On average, buying at that moment produced a one-year return of +171.5%. These dips have historically been decent entry points. These episodes lasted 56 weeks on average.
Is TWST a good value right now?
Here's what our data says about TWST as of 2026-06-19: The stock is above its 200-week moving average, so it doesn't currently meet our primary signal. The 14-week RSI is 80 (overbought). Free cash flow is currently negative. Return on equity is -18.2%. Price-to-book is 12.0x. This is not a buy or sell recommendation — always do your own research.
How does TWST compare to the S&P 500?
Over the past 6.8 years, $100 invested in TWST would have grown to $346, compared to $271 for the S&P 500. That's 20.2% annualized vs 15.9% for the index. TWST has outperformed the broader market over this period.
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of week of 2026-06-19