OPK
OPKO Health, Inc. Healthcare - Diagnostics & Research Investor Relations →
OPKO Health, Inc. (OPK) closed at $1.24 as of 2026-02-02, trading 21.5% below its 200-week moving average of $1.58. This places OPK in the extreme value zone. The stock is currently moving closer to the line, down from -20.8% last week. The 14-week RSI sits at 40, indicating neutral momentum.
Over the past 1531 weeks of data, OPK has crossed below its 200-week moving average 26 times. On average, these episodes lasted 32 weeks. Historically, investors who bought OPK at the start of these episodes saw an average one-year return of +19.5%.
With a market cap of $984 million, OPK is a small-cap stock. Free cash flow yield is currently negative, meaning the company is burning cash. Return on equity stands at -13.3%. The stock trades at 0.7x book value.
Over the past 29.4 years, a hypothetical investment of $100 in OPK would have grown to $45, compared to $1617 for the S&P 500. OPK has returned -2.7% annualized vs 9.9% for the index, underperforming the broader market over this period.
Free cash flow has been declining at a -100% compound annual rate. A deteriorating cash flow trend warrants extra scrutiny — the stock may be cheap for a reason.
Growth of $100: OPK vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After OPK Crosses Below the Line?
Across 26 historical episodes, buying OPK when it crossed below its 200-week moving average produced an average return of +15.6% after 12 months (median +8.0%), compared to +12.4% for the S&P 500 over the same periods. 58% of those episodes were profitable after one year. After 24 months, the average return was +16.3% vs +20.6% for the index.
Each line shows $100 invested at the moment OPK crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
OPK has crossed below its 200-week MA 26 times with an average 1-year return of +19.5% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Oct 1996 | Aug 1997 | 43 | 40.2% | +137.0% | -63.3% |
| Aug 1997 | Sep 1997 | 3 | 5.2% | +79.3% | -65.8% |
| Aug 1998 | Sep 1998 | 2 | 28.7% | +86.9% | -67.5% |
| Oct 1998 | Oct 1998 | 2 | 6.6% | +25.6% | -75.2% |
| Nov 1998 | Dec 1998 | 3 | 9.2% | +15.5% | -76.4% |
| Jun 1999 | Jun 1999 | 1 | 3.5% | +41.7% | -77.3% |
| Apr 2000 | Apr 2000 | 1 | 22.0% | -21.2% | -75.5% |
| Dec 2000 | Jan 2001 | 3 | 3.7% | -67.0% | -82.6% |
| Jan 2001 | Aug 2006 | 291 | 92.9% | -67.7% | -83.3% |
| Jun 2008 | Jul 2008 | 2 | 16.2% | +37.8% | -2.4% |
| Sep 2008 | Jun 2009 | 37 | 64.3% | +53.1% | -14.5% |
| Jun 2009 | Jul 2009 | 3 | 11.1% | +25.7% | -29.1% |
| Nov 2009 | Apr 2010 | 19 | 19.8% | +80.8% | -27.9% |
| May 2010 | Jun 2010 | 6 | 12.6% | +100.5% | -33.7% |
| Jun 2010 | Jul 2010 | 1 | 0.2% | +69.1% | -43.6% |
| Aug 2010 | Oct 2010 | 8 | 8.2% | +78.8% | -42.9% |
| Jan 2016 | Feb 2016 | 6 | 10.5% | +11.2% | -84.9% |
| Jun 2016 | Jun 2016 | 1 | 2.9% | -27.8% | -86.3% |
| Aug 2016 | Sep 2016 | 2 | 4.9% | -32.8% | -86.4% |
| Oct 2016 | Nov 2016 | 5 | 4.3% | -26.5% | -86.9% |
| Dec 2016 | Jul 2020 | 185 | 77.0% | -47.3% | -86.7% |
| Aug 2020 | Oct 2020 | 6 | 30.3% | +15.6% | -62.9% |
| Oct 2020 | Nov 2020 | 4 | 13.0% | +7.7% | -64.8% |
| Jul 2021 | Aug 2021 | 1 | 0.4% | -31.4% | -64.0% |
| Jan 2022 | Mar 2022 | 7 | 11.5% | -57.3% | -58.0% |
| Apr 2022 | Ongoing | 199+ | 68.9% | Ongoing | -57.7% |
| Average | 32 | — | +19.5% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02