OMER
Omeros Corporation Healthcare - Biotechnology Investor Relations →
Omeros Corporation (OMER) closed at $11.00 as of 2026-03-20, trading 109.5% above its 200-week moving average of $5.25. The stock is currently moving closer to the line, down from 114.8% last week. The 14-week RSI sits at 53, indicating neutral momentum.
Trading activity has gone quiet — just 0.5x of its usual 14-week average. But the buying that is happening outweighs the selling (1.46 buyers-vs-sellers ratio). When volume dries up but buyers are still showing up more than sellers, it can mean the worst of the selling is over and the stock is quietly building a floor.
Over the past 810 weeks of data, OMER has crossed below its 200-week moving average 17 times. On average, these episodes lasted 26 weeks.
With a market cap of $780 million, OMER is a small-cap stock. Free cash flow yield is currently negative, meaning the company is burning cash. The stock trades at -3.5x book value.
The company has been aggressively buying back shares, reducing its share count by 7.3% over the past three years.
Over the past 15.6 years, a hypothetical investment of $100 in OMER would have grown to $152, compared to $753 for the S&P 500. OMER has returned 2.7% annualized vs 13.8% for the index, underperforming the broader market over this period.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Business Health
Annual financials — how the underlying business has performed over the past several years.
Cash Flow Free cash flow & net income ($M)
Revenue Annual revenue ($M) — business growth proxy
Total Debt Balance sheet debt ($M)
ROIC Return on invested capital (%)
FCF Yield Free cash flow / market cap (%) — Yartseva signal
Gross Margin Pricing power & competitive moat (%)
Shares Outstanding Buybacks vs dilution (millions)
Growth of $100: OMER vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After OMER Crosses Below the Line?
Across 17 historical episodes, buying OMER when it crossed below its 200-week moving average produced an average return of +0.6% after 12 months (median -1.0%), compared to +14.1% for the S&P 500 over the same periods. 44% of those episodes were profitable after one year. After 24 months, the average return was +18.2% vs +34.1% for the index.
Each line shows $100 invested at the moment OMER crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
OMER has crossed below its 200-week MA 17 times
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Jan 2011 | Jan 2012 | 53 | 50.1% | -6.7% | +76.3% |
| Nov 2012 | Nov 2012 | 1 | 6.1% | +23.4% | +73.0% |
| Dec 2012 | Sep 2013 | 40 | 41.2% | +26.7% | +69.0% |
| Jan 2016 | Mar 2016 | 9 | 18.9% | -13.5% | -4.3% |
| May 2016 | Nov 2016 | 28 | 42.3% | +24.1% | -11.1% |
| Nov 2016 | Mar 2017 | 17 | 30.3% | +90.1% | +0.8% |
| Oct 2017 | Nov 2017 | 1 | 1.8% | +9.4% | -26.4% |
| Jan 2018 | Apr 2018 | 13 | 36.1% | -10.3% | -27.6% |
| Oct 2018 | Oct 2018 | 3 | 14.0% | +14.7% | -21.3% |
| Nov 2018 | Mar 2019 | 17 | 31.1% | +4.3% | -15.5% |
| Jul 2019 | Jul 2019 | 3 | 3.7% | +3.1% | -25.1% |
| Oct 2019 | Oct 2019 | 1 | 0.7% | -27.7% | -28.2% |
| Nov 2019 | Apr 2020 | 24 | 28.7% | -23.1% | -19.0% |
| May 2020 | Jan 2021 | 35 | 37.3% | +29.2% | -21.9% |
| May 2021 | Sep 2021 | 17 | 15.1% | -81.1% | -26.1% |
| Sep 2021 | Nov 2024 | 163 | 88.4% | -63.1% | +28.8% |
| May 2025 | Oct 2025 | 22 | 41.9% | N/A | +241.6% |
Frequently Asked Questions
Is OMER below its 200-week moving average?
No. Omeros Corporation (OMER) is currently 109.5% above its 200-week moving average of $5.25. It would need to fall to $5.25 to cross below the line.
What is OMER's 200-week moving average price?
Omeros Corporation's 200-week moving average is $5.25 as of 2026-03-20. This is the average weekly closing price over roughly the last 4 years, and it acts as a long-term trend line. When a stock drops below this level, it can signal that the price has fallen far enough from the long-term trend to attract value-oriented investors.
What happens when OMER drops below its 200-week moving average?
OMER has crossed below its 200-week moving average 17 times in our data. These episodes lasted 26 weeks on average.
Is OMER a good value right now?
Here's what our data says about OMER as of 2026-03-20: The stock is above its 200-week moving average, so it doesn't currently meet our primary signal. The 14-week RSI is 53. Free cash flow is currently negative. Price-to-book is -3.5x. This is not a buy or sell recommendation — always do your own research.
How does OMER compare to the S&P 500?
Over the past 15.6 years, $100 invested in OMER would have grown to $152, compared to $753 for the S&P 500. That's 2.7% annualized vs 13.8% for the index. OMER has underperformed the broader market over this period.
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of week of 2026-03-20