NBIX

Neurocrine Biosciences Inc. Healthcare - Biotechnology Investor Relations →

NO
17.6% ABOVE
↑ Moving away Was 13.5% last week
-15% -10% -5% 0% 5% 10% 15%+
Buy Threshold $120.06
14-Week RSI 48

Neurocrine Biosciences Inc. (NBIX) closed at $141.20 as of 2026-02-02, trading 17.6% above its 200-week moving average of $120.06. The stock moved further from the line this week, up from 13.5% last week. The 14-week RSI sits at 48, indicating neutral momentum.

Over the past 1502 weeks of data, NBIX has crossed below its 200-week moving average 17 times. On average, these episodes lasted 26 weeks. The average one-year return after crossing below was -5.7%, suggesting these dips have not historically been reliable buying opportunities for this stock.

With a market cap of $14.1 billion, NBIX is a large-cap stock. The company generates a free cash flow yield of 2.5%. Return on equity stands at 15.0%, a solid level. The stock trades at 4.7x book value.

Share count has increased 4.7% over three years, indicating dilution.

Over the past 28.9 years, a hypothetical investment of $100 in NBIX would have grown to $1807, compared to $1418 for the S&P 500. That represents an annualized return of 10.5% vs 9.6% for the index — confirming NBIX as a market-beating investment and the kind of quality company where buying during 200-week moving average touches has historically been rewarded.

Free cash flow has been growing at a 33.7% compound annual rate, with 4 consecutive years of positive cash generation.

Growth of $100: NBIX vs S&P 500

Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.

What Happens After NBIX Crosses Below the Line?

Across 17 historical episodes, buying NBIX when it crossed below its 200-week moving average produced an average return of -2.3% after 12 months (median +1.0%), compared to +12.1% for the S&P 500 over the same periods. 56% of those episodes were profitable after one year. After 24 months, the average return was -18.5% vs +27.4% for the index.

Each line shows $100 invested at the moment NBIX crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.

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Historical Touches

NBIX has crossed below its 200-week MA 17 times with an average 1-year return of +-5.7% after recovery.

Crossed BelowRecoveredWeeksMax Depth1-Year ReturnReturn Since Touch
Apr 1997Sep 19972020.7%-2.4%+1707.4%
Sep 1997Oct 199710.4%-42.9%+1367.0%
Oct 1997Nov 199910651.0%-27.6%+1386.3%
Aug 2004Aug 200412.7%+14.6%+242.0%
Feb 2005Jul 20052122.8%+46.7%+241.3%
Aug 2005Sep 200541.8%-80.1%+213.0%
Sep 2005Sep 200510.1%-76.7%+207.5%
May 2006Sep 201022790.4%-41.5%+620.4%
May 2021May 202112.7%-12.6%+55.1%
May 2021Jun 202110.1%+1.2%+49.6%
Jul 2021Sep 2021117.6%+0.2%+48.6%
Nov 2021Apr 20222223.3%+30.7%+51.5%
Apr 2022Jun 2022918.7%+11.3%+50.8%
Jul 2022Aug 202242.5%-1.6%+47.7%
Mar 2023Mar 202336.0%+45.3%+47.4%
May 2023Jul 2023129.7%+44.5%+45.0%
Mar 2025May 2025518.0%N/A+47.6%
Average26+-5.7%

Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.

Data as of Friday close, 2026-02-02