MIRM
Mirum Pharmaceuticals, Inc. Healthcare - Biotechnology Investor Relations →
Mirum Pharmaceuticals, Inc. (MIRM) closed at $100.47 as of 2026-02-02, trading 167.0% above its 200-week moving average of $37.63. The stock is currently moving closer to the line, down from 177.0% last week. With a 14-week RSI of 72, MIRM is in overbought territory.
Over the past 294 weeks of data, MIRM has crossed below its 200-week moving average 5 times. On average, these episodes lasted 6 weeks. Historically, investors who bought MIRM at the start of these episodes saw an average one-year return of +32.5%.
With a market cap of $6.0 billion, MIRM is a mid-cap stock. The company generates a free cash flow yield of 0.8%. Return on equity stands at -15.8%. The stock trades at 17.6x book value.
Share count has increased 58.1% over three years, indicating dilution.
Over the past 5.8 years, a hypothetical investment of $100 in MIRM would have grown to $499, compared to $243 for the S&P 500. That represents an annualized return of 32.2% vs 16.7% for the index — confirming MIRM as a market-beating investment and the kind of quality company where buying during 200-week moving average touches has historically been rewarded.
In the past 12 months, corporate insiders have made 5 open-market purchases totaling $12,672,180. Multiple insiders purchased within a 30-day window — a cluster buy pattern that historically signals management confidence in the company's prospects.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Growth of $100: MIRM vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After MIRM Crosses Below the Line?
Across 5 historical episodes, buying MIRM when it crossed below its 200-week moving average produced an average return of +33.0% after 12 months (median +45.0%), compared to +8.6% for the S&P 500 over the same periods. 100% of those episodes were profitable after one year. After 24 months, the average return was +72.8% vs +16.6% for the index.
Each line shows $100 invested at the moment MIRM crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
MIRM has crossed below its 200-week MA 5 times with an average 1-year return of +32.5% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Oct 2020 | Nov 2020 | 1 | 0.8% | +0.8% | +537.9% |
| May 2021 | Jun 2021 | 2 | 2.2% | +49.7% | +507.4% |
| Jun 2021 | Aug 2021 | 9 | 15.6% | +19.3% | +499.8% |
| Oct 2021 | Jan 2022 | 14 | 20.9% | +11.7% | +502.3% |
| Dec 2022 | Dec 2022 | 3 | 0.6% | +80.9% | +453.2% |
| Average | 6 | — | +32.5% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02