KRYS
Krystal Biotech Inc. Healthcare - Biotechnology Investor Relations →
Krystal Biotech Inc. (KRYS) closed at $272.74 as of 2026-02-02, trading 100.0% above its 200-week moving average of $136.40. The stock is currently moving closer to the line, down from 106.3% last week. With a 14-week RSI of 82, KRYS is in overbought territory.
Over the past 389 weeks of data, KRYS has crossed below its 200-week moving average 1 time. On average, these episodes lasted 1 weeks. Historically, investors who bought KRYS at the start of these episodes saw an average one-year return of +97.7%.
With a market cap of $7.9 billion, KRYS is a mid-cap stock. The company generates a free cash flow yield of 1.0%. Return on equity stands at 19.7%, a solid level. The stock trades at 7.0x book value.
Share count has increased 14.2% over three years, indicating dilution. KRYS passes our Buffett quality screen: high return on equity, low debt, and positive free cash flow.
Over the past 7.6 years, a hypothetical investment of $100 in KRYS would have grown to $1659, compared to $267 for the S&P 500. That represents an annualized return of 44.8% vs 13.8% for the index — confirming KRYS as a market-beating investment and the kind of quality company where buying during 200-week moving average touches has historically been rewarded.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Growth of $100: KRYS vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After KRYS Crosses Below the Line?
Across 1 historical episodes, buying KRYS when it crossed below its 200-week moving average produced an average return of +14.0% after 12 months (median +14.0%), compared to -9.0% for the S&P 500 over the same periods. 100% of those episodes were profitable after one year. After 24 months, the average return was +56.0% vs +3.0% for the index.
Each line shows $100 invested at the moment KRYS crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
KRYS has crossed below its 200-week MA 1 time with an average 1-year return of +97.7% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Nov 2021 | Nov 2021 | 1 | 3.7% | +97.7% | +585.1% |
| Average | 1 | — | +97.7% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02