IOVA
Iovance Biotherapeutics, Inc. Healthcare - Biotechnology Investor Relations →
Iovance Biotherapeutics, Inc. (IOVA) closed at $3.69 as of 2026-03-20, trading 46.0% below its 200-week moving average of $6.83. This places IOVA in the extreme value zone. The stock is currently moving closer to the line, down from -42.5% last week. The 14-week RSI sits at 63, indicating neutral momentum.
Trading volume is running at 1.2x of its 14-week average, which is in the normal range. The balance between buying and selling volume (1.08 ratio) is neutral — neither side is clearly dominating.
Over the past 757 weeks of data, IOVA has crossed below its 200-week moving average 16 times. On average, these episodes lasted 32 weeks. Historically, investors who bought IOVA at the start of these episodes saw an average one-year return of +27.6%.
With a market cap of $1520 million, IOVA is a small-cap stock. Free cash flow yield is currently negative, meaning the company is burning cash. Return on equity stands at -55.5%. The stock trades at 2.2x book value.
Share count has increased 119.3% over three years, indicating dilution.
Over the past 14.6 years, a hypothetical investment of $100 in IOVA would have grown to $4, compared to $744 for the S&P 500. IOVA has returned -20.2% annualized vs 14.8% for the index, underperforming the broader market over this period.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Business Health
Annual financials — how the underlying business has performed over the past several years.
Cash Flow Free cash flow & net income ($M)
Revenue Annual revenue ($M) — business growth proxy
Total Debt Balance sheet debt ($M)
ROIC Return on invested capital (%)
FCF Yield Free cash flow / market cap (%) — Yartseva signal
Gross Margin Pricing power & competitive moat (%)
Shares Outstanding Buybacks vs dilution (millions)
Growth of $100: IOVA vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After IOVA Crosses Below the Line?
Across 16 historical episodes, buying IOVA when it crossed below its 200-week moving average produced an average return of +19.0% after 12 months (median +26.0%), compared to +14.8% for the S&P 500 over the same periods. 56% of those episodes were profitable after one year. After 24 months, the average return was +56.9% vs +29.4% for the index.
Each line shows $100 invested at the moment IOVA crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
IOVA has crossed below its 200-week MA 16 times with an average 1-year return of +27.6% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Sep 2011 | Oct 2011 | 5 | 19.0% | -72.2% | -96.2% |
| Nov 2011 | Feb 2012 | 11 | 21.9% | -66.1% | -96.7% |
| Feb 2012 | Apr 2012 | 6 | 12.9% | -93.2% | -96.8% |
| Apr 2012 | Jul 2016 | 222 | 98.8% | -97.6% | -95.7% |
| Oct 2016 | Nov 2016 | 4 | 18.4% | +15.0% | -41.9% |
| Nov 2016 | Dec 2016 | 2 | 14.7% | +46.7% | -38.5% |
| Dec 2016 | Jan 2017 | 1 | 1.0% | +15.1% | -46.9% |
| Jan 2017 | Jan 2017 | 1 | 0.9% | +95.7% | -47.3% |
| Apr 2017 | Sep 2017 | 23 | 36.5% | +111.5% | -43.7% |
| Oct 2017 | Oct 2017 | 3 | 2.6% | +63.4% | -49.5% |
| Oct 2018 | Nov 2018 | 3 | 0.6% | +127.9% | -59.0% |
| Dec 2018 | Dec 2018 | 4 | 17.1% | +175.6% | -58.9% |
| Jan 2019 | Jan 2019 | 1 | 0.4% | +148.0% | -58.9% |
| May 2021 | Jun 2021 | 3 | 16.0% | -14.5% | -79.6% |
| Aug 2021 | Aug 2021 | 2 | 5.0% | -41.8% | -83.1% |
| Nov 2021 | Ongoing | 228+ | 84.3% | Ongoing | -82.5% |
| Average | 32 | — | +27.6% | — |
Frequently Asked Questions
Is IOVA below its 200-week moving average?
Yes. As of 2026-03-20, Iovance Biotherapeutics, Inc. (IOVA) is trading 46.0% below its 200-week moving average of $6.83. The current price is $3.69.
What is IOVA's 200-week moving average price?
Iovance Biotherapeutics, Inc.'s 200-week moving average is $6.83 as of 2026-03-20. This is the average weekly closing price over roughly the last 4 years, and it acts as a long-term trend line. When a stock drops below this level, it can signal that the price has fallen far enough from the long-term trend to attract value-oriented investors.
What happens when IOVA drops below its 200-week moving average?
IOVA has crossed below its 200-week moving average 16 times in our data. On average, buying at that moment produced a one-year return of +27.6%. These dips have historically been decent entry points. These episodes lasted 32 weeks on average.
Is IOVA a good value right now?
Here's what our data says about IOVA as of 2026-03-20: The stock is below its 200-week moving average, which is the starting point for our analysis. The 14-week RSI is 63. Free cash flow is currently negative. Return on equity is -55.5%. Price-to-book is 2.2x. This is not a buy or sell recommendation — always do your own research.
How does IOVA compare to the S&P 500?
Over the past 14.6 years, $100 invested in IOVA would have grown to $4, compared to $744 for the S&P 500. That's -20.2% annualized vs 14.8% for the index. IOVA has underperformed the broader market over this period.
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of week of 2026-03-20