EXEL
Exelixis Inc. Healthcare - Biotechnology Investor Relations →
Exelixis Inc. (EXEL) closed at $43.90 as of 2026-02-02, trading 63.3% above its 200-week moving average of $26.89. The stock moved further from the line this week, up from 54.4% last week. The 14-week RSI sits at 61, indicating neutral momentum.
Over the past 1298 weeks of data, EXEL has crossed below its 200-week moving average 23 times. On average, these episodes lasted 31 weeks. Historically, investors who bought EXEL at the start of these episodes saw an average one-year return of +36.9%.
With a market cap of $11.8 billion, EXEL is a large-cap stock. The company generates a free cash flow yield of 4.6%. Return on equity stands at 30.6%, indicating strong profitability. The stock trades at 5.5x book value.
The company has been aggressively buying back shares, reducing its share count by 11.6% over the past three years. EXEL passes our Buffett quality screen: high return on equity, low debt, and positive free cash flow.
Over the past 25 years, a hypothetical investment of $100 in EXEL would have grown to $505, compared to $930 for the S&P 500. EXEL has returned 6.7% annualized vs 9.3% for the index, underperforming the broader market over this period.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Growth of $100: EXEL vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After EXEL Crosses Below the Line?
Across 23 historical episodes, buying EXEL when it crossed below its 200-week moving average produced an average return of +43.3% after 12 months (median +15.0%), compared to +12.2% for the S&P 500 over the same periods. 65% of those episodes were profitable after one year. After 24 months, the average return was +54.4% vs +25.2% for the index.
Each line shows $100 invested at the moment EXEL crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
EXEL has crossed below its 200-week MA 23 times with an average 1-year return of +36.9% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Mar 2001 | Dec 2004 | 194 | 81.4% | +58.7% | +405.3% |
| Jan 2005 | Jul 2005 | 26 | 31.0% | +20.8% | +409.9% |
| Aug 2005 | Oct 2005 | 12 | 9.6% | -6.0% | +445.3% |
| Aug 2006 | Aug 2006 | 3 | 7.4% | +32.2% | +479.9% |
| Nov 2007 | Dec 2007 | 5 | 11.9% | -61.5% | +384.0% |
| Dec 2007 | Dec 2010 | 155 | 72.1% | -44.4% | +394.9% |
| Aug 2011 | Aug 2011 | 1 | 4.8% | -28.8% | +613.8% |
| Sep 2011 | Jul 2012 | 43 | 36.7% | -10.2% | +609.2% |
| Jul 2012 | Dec 2013 | 73 | 28.9% | -5.9% | +686.7% |
| Mar 2014 | Jul 2015 | 69 | 75.5% | -24.9% | +1198.8% |
| Jan 2016 | Jan 2016 | 1 | 4.9% | +337.6% | +937.8% |
| Feb 2016 | Apr 2016 | 10 | 13.1% | +425.7% | +945.2% |
| Sep 2019 | Feb 2020 | 20 | 15.6% | +32.4% | +143.9% |
| Feb 2020 | Apr 2020 | 8 | 24.1% | +16.5% | +136.1% |
| Aug 2020 | Sep 2020 | 1 | 3.7% | -4.4% | +112.4% |
| Oct 2020 | Jan 2021 | 10 | 13.2% | +5.0% | +114.4% |
| Feb 2021 | Mar 2021 | 1 | 0.5% | -6.8% | +102.7% |
| Jun 2021 | Sep 2021 | 13 | 22.4% | +18.1% | +140.4% |
| Nov 2021 | Feb 2022 | 17 | 23.8% | -15.0% | +126.8% |
| May 2022 | Jun 2022 | 6 | 13.3% | -4.5% | +118.6% |
| Aug 2022 | Jul 2023 | 51 | 25.2% | +10.5% | +125.4% |
| Oct 2023 | Oct 2023 | 1 | 0.0% | +38.0% | +117.3% |
| Feb 2024 | Feb 2024 | 2 | 1.4% | +65.6% | +117.1% |
| Average | 31 | — | +36.9% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02