APLS
Apellis Pharmaceuticals, Inc. Healthcare - Biotechnology Investor Relations →
Apellis Pharmaceuticals, Inc. (APLS) closed at $23.49 as of 2026-02-02, trading 46.2% below its 200-week moving average of $43.71. This places APLS in the extreme value zone. The stock moved further from the line this week, up from -48.5% last week. The 14-week RSI sits at 54, indicating neutral momentum.
Over the past 382 weeks of data, APLS has crossed below its 200-week moving average 5 times. On average, these episodes lasted 27 weeks. Historically, investors who bought APLS at the start of these episodes saw an average one-year return of +71.7%.
With a market cap of $3.0 billion, APLS is a mid-cap stock. The company generates a free cash flow yield of 1.7%. Return on equity stands at 14.1%. The stock trades at 7.4x book value.
Share count has increased 27.7% over three years, indicating dilution.
Over the past 7.4 years, a hypothetical investment of $100 in APLS would have grown to $157, compared to $285 for the S&P 500. APLS has returned 6.2% annualized vs 15.2% for the index, underperforming the broader market over this period.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Growth of $100: APLS vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After APLS Crosses Below the Line?
Across 5 historical episodes, buying APLS when it crossed below its 200-week moving average produced an average return of +45.4% after 12 months (median +64.0%), compared to +9.2% for the S&P 500 over the same periods. 80% of those episodes were profitable after one year. After 24 months, the average return was +85.8% vs +29.8% for the index.
Each line shows $100 invested at the moment APLS crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
APLS has crossed below its 200-week MA 5 times with an average 1-year return of +71.7% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Oct 2018 | Feb 2019 | 19 | 31.4% | +107.1% | +74.8% |
| May 2019 | May 2019 | 1 | 1.2% | +72.2% | +30.5% |
| Oct 2021 | Nov 2021 | 1 | 0.5% | +97.1% | -23.6% |
| Jul 2023 | Nov 2023 | 19 | 48.3% | +10.4% | -31.7% |
| Apr 2024 | Ongoing | 95+ | 64.4% | Ongoing | -50.6% |
| Average | 27 | — | +71.7% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02