ALNY
Alnylam Pharmaceuticals Inc. Healthcare - Biotechnology Investor Relations →
Alnylam Pharmaceuticals Inc. (ALNY) closed at $328.16 as of 2026-02-02, trading 36.2% above its 200-week moving average of $241.00. The stock is currently moving closer to the line, down from 40.8% last week. With a 14-week RSI of 16, ALNY is in oversold territory.
Over the past 1083 weeks of data, ALNY has crossed below its 200-week moving average 15 times. On average, these episodes lasted 20 weeks. Historically, investors who bought ALNY at the start of these episodes saw an average one-year return of +23.0%.
With a market cap of $43.4 billion, ALNY is a large-cap stock. The company generates a free cash flow yield of 0.2%. Return on equity stands at 32.7%, indicating strong profitability. The stock trades at 184.9x book value.
Share count has increased 7.6% over three years, indicating dilution.
Over the past 20.8 years, a hypothetical investment of $100 in ALNY would have grown to $4533, compared to $849 for the S&P 500. That represents an annualized return of 20.1% vs 10.8% for the index — confirming ALNY as a market-beating investment and the kind of quality company where buying during 200-week moving average touches has historically been rewarded.
Free cash flow has been volatile over the past several years, making the quality of earnings harder to assess.
Growth of $100: ALNY vs S&P 500
Monthly data normalized to $100 at start. Vertical dashed lines mark 200-week MA touches.
What Happens After ALNY Crosses Below the Line?
Across 15 historical episodes, buying ALNY when it crossed below its 200-week moving average produced an average return of +17.7% after 12 months (median +3.0%), compared to +19.4% for the S&P 500 over the same periods. 53% of those episodes were profitable after one year. After 24 months, the average return was +42.2% vs +40.9% for the index.
Each line shows $100 invested at the moment ALNY crossed below its 200-week MA. Bold blue = stock average. Gray dashed = S&P 500 average over same periods.
Historical Touches
ALNY has crossed below its 200-week MA 15 times with an average 1-year return of +23.0% after recovery.
| Crossed Below | Recovered | Weeks | Max Depth | 1-Year Return | Return Since Touch |
|---|---|---|---|---|---|
| Nov 2008 | Dec 2008 | 2 | 5.6% | -6.3% | +1726.2% |
| Feb 2009 | Jun 2009 | 15 | 21.3% | -10.4% | +1591.5% |
| Jul 2009 | Jul 2009 | 2 | 7.0% | -18.6% | +1573.4% |
| Sep 2009 | Jul 2012 | 146 | 66.6% | -43.7% | +1421.4% |
| Feb 2016 | Mar 2016 | 7 | 8.2% | -23.5% | +451.1% |
| May 2016 | May 2016 | 3 | 20.4% | -0.9% | +490.7% |
| Jun 2016 | Aug 2016 | 8 | 19.3% | +15.3% | +419.5% |
| Aug 2016 | Sep 2016 | 2 | 0.9% | +28.5% | +374.4% |
| Sep 2016 | Jun 2017 | 37 | 52.7% | +73.3% | +384.2% |
| Sep 2017 | Sep 2017 | 2 | 3.2% | +47.9% | +345.3% |
| Sep 2018 | Mar 2019 | 26 | 27.2% | -7.3% | +275.0% |
| Apr 2019 | Sep 2019 | 21 | 18.8% | +68.7% | +299.9% |
| Sep 2019 | Oct 2019 | 2 | 4.6% | +76.2% | +326.1% |
| Oct 2023 | Nov 2023 | 6 | 9.0% | +82.9% | +102.8% |
| Feb 2024 | Jun 2024 | 20 | 16.7% | +62.4% | +93.0% |
| Average | 20 | — | +23.0% | — |
Not financial advice. This is an educational tool. Past performance does not guarantee future results. Do your own research before making investment decisions.
Data as of Friday close, 2026-02-02